A randomized study of midazolam versus dexmedetomidine for premedication in children via intranasal mucosal atomization device
نویسندگان
چکیده
Many drugs have been tried for premedication in children[1] amongst which midazolam and dexmedetomidine are commonly used reportedly safe effective usage during both separation as well induction of anaesthesia. Hence, we planned to carry out a study versus children via intranasal Mucosal Atomization Device. To compare the efficacy 2 6 years age This randomized was done at Dhiraj hospital, Piparia, Vadodara, Gujarat on 60 belonging American Society Anaesthesiologists (ASA) physical status I or II 2-6 either gender undergoing elective surgeries under general Children were separated into: Group M - Midazolam 0.2 mg/kg (preservative free) D Dexmedetomidine 1µg/kg. Drug administered 30 minutes prior surgery following parameters assessed: Acceptance drug, Sedation Score, behaviour parental mask acceptance. statistically significantly better aspect drug acceptance, sedation after administration, acceptance than midazolam.
منابع مشابه
Pre anaesthetic medication in children: A comparison of intranasal dexmedetomidine versus intranasal midazolam
Background & objectives: Children are more anxious and fearful due to their limited cognitive capabilities, lack of understanding of health care system and lack of self control. It becomes an important concern for an anaesthesiologist to relieve their pre-operative anxiety. Midazolam is frequently used as premedication agent in children. New drugs such as the alpha-2 agonists have also been int...
متن کاملA comparison of intranasal dexmedetomidine and oral midazolam for premedication in pediatric anesthesia: a double-blinded randomized controlled trial.
BACKGROUND Midazolam is the most commonly used premedication in children. It has been shown to be more effective than parental presence or placebo in reducing anxiety and improving compliance at induction of anesthesia. Clonidine, an alpha(2) agonist, has been suggested as an alternative. Dexmedetomidine is a more alpha(2) selective drug with more favorable pharmacokinetic properties than cloni...
متن کاملDexmedetomidine versus Midazolam as Premedication in Anesthesia: A Meta-Analysis from Randomized Controlled Clinical Trials
Dexmedetomidine [Dex] is an α2-adrenoceptor agonist which provides sedation, analgesia and anxiolytic effects, thus making it a potentially useful anesthetic premedication. A number of clinical trials have been conducted to compare the sedative effect of Dex versus midazolam [Mdz], a conventional sedative agent in anesthesia. Nevertheless, consensus has not been achieved on which agent is super...
متن کاملIntranasal clonidine vs. midazolam as premedication in children: a randomized controlled trial.
OBJECTIVE To compare anxiolysis produced by intranasal clonidine with intranasal midazolam as premedication in children undergoing surgery. DESIGN Double-blind randomized controlled study. SETTING Tertiary-care hospital, July 2009 to June 2010. PATIENTS 60 American Society of Anesthesiologists physical status I-II surgical patients aged 1-10 yr. INTERVENTION Participants randomly alloca...
متن کاملComparison of Intranasal dexmedetomidine and oral midazolam as premedication for cardiac catheterization procedure in pediatric patients
Objective: The aim of study is to evaluate the preoperative sedative effects of intranasal dexmedetomidine as compared to oral midazolam as preanesthetic medication in children undergoing cardiac catheterization for diagnostic and/or therapeutic procedure. Design: Prospective, randomized, double-blind, controlled study. Method: 61 patients of either sex between the ages 2-10 years were recruite...
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ژورنال
عنوان ژورنال: International Journal of Health Sciences (IJHS)
سال: 2022
ISSN: ['2550-6978', '2550-696X']
DOI: https://doi.org/10.53730/ijhs.v6ns3.5702